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Blood sugar
Blood sugar
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Metformin, explainedMetformin is a biguanide — an oral medicine prescribed since the 1950s and now one of the most studied drugs in medicine. It works on how your body handles glucose, not on appetite.
Less from the liverYour liver makes and releases less glucose overnight, which is where most fasting blood sugar comes from.
Better insulin responseYour cells respond to the insulin you already make, so the same glucose does more work.
Slower absorptionGlucose moves out of the gut more gradually, flattening the spike after a meal.
What to expect
FIRST 2 WEEKSThe first two weeksOne tablet with your evening meal. If your stomach objects, it happens here and it usually settles. Never take it on an empty stomach.
WEEKS 3–12Stepping upYour provider raises the dose on a set schedule, and only if you are tolerating the one before it. This is the stretch where most of the change happens.
ONGOINGHolding steadyYou settle at the dose that works and stay there. Check-ins continue, and you can change plans, pause or stop from your dashboard at any time.
Questions about metformin?
Zuma knows this treatment, who it suits, and who tends not to qualify. No account needed.Is this right for me?
Will it upset my stomach?
Can I take it long term?
Ask something else
The Malibu Protocol standardWe stand behind every treatment. No grey market. No research-only.
Physician-led care
Treatments are prescribed by a licensed clinician based on your intake.
MDIndependent licensed U.S. pharmacies
Every prescription is dispensed by an independent licensed U.S. pharmacy.
USPCompounded in the USA
Made to order at the dose your clinician prescribed.
FDAOnly what's clinically appropriate
We only offer treatments that are legitimately available to prescribe.
503AWho it isn't forSay so in your intake if any of these apply.
Conditions we screen for
Metformin carries a boxed warning for lactic acidosis — rare, but far more likely with reduced kidney function. Your provider checks kidney function before prescribing and periodically after.
None of this rules you out on its own. A provider reads your intake, and if metformin isn't the right fit they will say so and point you at what is.Check if I qualify — 2 minutes
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Questions, answered
Do I need a prescription?
How much do I take?
What if my stomach doesn't tolerate it?
Is metformin FDA-approved?
Can I pause or stop?
Will it help me lose weight?
Not sure which one?Not a problem. Answer a few questions online — no calls, no appointment. A licensed provider reads them and decides what fits. Nothing is prescribed or charged until they do.Get started
Or ask Zuma first
Metformin is an FDA-approved prescription medicine. Prescribing it for metabolic or longevity goals in people without type 2 diabetes is off-label — legal and common, and at the discretion of a US-licensed provider after review of your intake. This page is for information only and is not medical advice.
Metformin · monthly$89/mo
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