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Tirzepatide, explainedTirzepatide is a dual GIP and GLP-1 receptor agonist — it imitates two gut hormones rather than one. Both are released when you eat and both tell the brain the meal is over.
Two pathwaysGIP and GLP-1 act on appetite by different routes, which is why it is often tried when one alone has not suited.
Slows digestionThe stomach empties more gradually, so a meal satisfies for longer.
Steadies blood sugarFewer spikes after eating, which flattens the crash that follows.
What to expect
WEEKS 1–4Starting lowYou begin at the smallest dose. Appetite usually changes before anything else does.
WEEKS 5–12Stepping upYour provider raises the dose on a set schedule, and only if you are tolerating the one before it.
ONGOINGHolding steadyYou settle at the dose that works. Check-ins continue and you can change plans or stop.
Questions about tirzepatide?
Zuma knows this treatment, who it suits, and who tends not to qualify. No account needed.Is this right for me?
How is it different from semaglutide?
What are the side effects?
Ask something else
The Malibu Protocol standardWe stand behind every treatment. No grey market. No research-only.
Physician-led care
Treatments are prescribed by a licensed clinician based on your intake.
MDIndependent licensed U.S. pharmacies
Every prescription is dispensed by an independent licensed U.S. pharmacy.
USPCompounded in the USA
Made to order at the dose your clinician prescribed.
FDAOnly what's clinically appropriate
We only offer treatments that are legitimately available to prescribe.
503AWho it isn't forSay so in your intake if any of these apply.
Conditions we screen for
Tirzepatide carries a boxed warning for thyroid C-cell tumours in animal studies. Your provider screens for a personal or family history of medullary thyroid carcinoma and for MEN 2.
None of this rules you out on its own. A provider reads your intake, and if tirzepatide isn't the right fit they will say so.Check if I qualify — 2 minutes
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Questions, answered
Is compounded tirzepatide FDA-approved?
How is it different from semaglutide?
How is my dose decided?
What if it isn't right for me?
Can I pause or stop?
Do I need insurance?
Not sure which one?Not a problem. Answer a few questions online — no calls, no appointment. A licensed provider reads them and decides what fits. Nothing is prescribed or charged until they do.Get started
Or ask Zuma first
Compounded medications are not approved by the FDA. When prescribed, they are prepared and dispensed by an independent licensed U.S. pharmacy. This page is for information only and is not medical advice. Prescriptions are written at the discretion of a U.S.-licensed clinician after review of your intake.
Semaglutide · quarterly$212/mo
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